Diabetic Neuropathy Treatment » Autonomic

Cardiovascular Signals in Diabetes Mellitus: A New Tool to Detect Autonomic Neuropathy

admin — Fri, 12 Mar 2010 15:21:26 +0000

Product DescriptionEarly detection of sub-clinical autonomic dysfunction is of vital importance in patients with diabetes mellitus (DM) for the prevention of subsequent serious adverse consequences. Reduction in heart rate variability (HRV) is now regarded as the earliest indicator of cardiovascular dysregulation in DM. HRV has traditionally been quantified using linear measures, which describe the magnitude of RR interval oscillations, but are insufficient to characterise complex heart rate dynamics. While HRV is mostly mediated by parasympathetic nervous system, beat-to-beat blood pressure recordings may provide information regarding sympathetic activity. A variety of novel measures has been developed to quantify non-linear features of cardiovascular signals, providing information on the complexity of the dynamical system involved in the genesis of these short-term fluctuations. In this book, it is demonstrated that novel non-linear methods are often more sensitive to autonomic dysregulation than linear methods and therefore may improve the diagnostic power of cardiovascular variability analysis for cardiovascular autonomic neuropathy in DM. Our data indicate that cardiovascular dysregulation progresses in relatively short time frames, depending on the history of DM. Further, its progression appears to be associated with glycemic control. Different methods of cardiovascular variability analysis can provide mutually independent information and therefore should be used simultaneously for a comprehensive analysis of autonomic dysfunction to identify patients at risk for autonomic neuropathy.

Cardiovascular Signals in Diabetes Mellitus: A New Tool to Detect Autonomic Neuropathy

I Have Autonomic Neuropathy Caused By Diabetes And I Have Mottling On My Arms And Hands, What Causes This?

admin — Sun, 20 Dec 2009 15:22:33 +0000

I am a 21yr old female with autonomic neuropathy caused by diabetes, will this ever go away? what causes this? I have it a little bit on my lower legs as well but its much worse on my arms and hands, does anybody else have this?

Symptoms and Treatments of Diabetic Autonomic Neuropathy

admin — Sun, 22 Nov 2009 15:29:38 +0000

Diabetics need to fight not ony the disease but also various complications that it brings allong. Diabetic neuropathy is one such complication that is caused by poor blood supply and nerve damage to a diabetic’s body. One such silent complication that attacks from within the body is diabetic autonomic neuropathy. Here are the symptoms and treatments for diabetic autonomic neuropathy.
Over a period of time, high blood glucose fluctuations can lead to nerve damage and impaired blood circulation, which can result in specific organs of the body getting impaired or damaged. There are 4 types of diabetic neuropathy, namely peripheral, focal, proximal and lastly autonomic neuropathy that can affect different functions and organs of the body. Diabetic autonomic neuropathy affects the nerves related to the functioning of the heart, lungs, digestion, perspiration, bladder, bowels, salivation and vision. It is very difficult to diagnose the onset of this type of neuropathy since there is no associated tingling, pain or numbness, which is usually found in other types of neuropathy. Another problem in catching the symptoms is that it is sometimes confused with other minor ailments such as an upset stomach, etc.
The symptoms depend on the organs that get affected with the onset of diabetic autonomic neuropathy. Hence patients could develop gastrointestinal problems such as nausea, heartburn, vomiting, which in turn can also cause blood sugar levels to fluctuate wildly. Other symptoms include urinary tract infections and incontinence in case the urinary bladder is affected. In case the disease affects the patient’s sexual organs, then it could cause erectile dysfunction or vaginal dryness depending on the sex of the patient. This disease can also affect the sweat glands thus leading to excessive sweating or even extremely dry skin, which again can open the way for skin infections. Patients that have diabetic autonomic neuropathy can also become victims of hypoglycemic unawareness or even suffer silent heart attacks, which could prove to be extremely dangerous.
While medications and surgery can be used to treat specific cases of diabetic autonomic neuropathy, antioxidants such as alpha lipoic acid too have shown positive results in trials in Europe. This treatment can be used on humans and select pets such as dogs and hamsters although cats cannot be treated due to a toxic reaction by this antioxidant with its liver. Patients should also consume enough liquids to keep their skin hydrated and should also go in for smaller, low-fat and low-fiber meals to improve digestion and regularize bladder movements. Adequate exercises to build up muscle tissue and burn excess fat along with a strict insulin monitoring and delivery schedule is a must for diabetics that need to avoid the onset of diabetic neuropathy. Diabetics should also take adequate care of their skin and also observe the physical condition of their hands and feet on a daily basis.
Diabetics should regularly check-in for check-ups and consult their doctor before making any changes to their diet or insulin delivery schedules. Each medicine or injection should also be cleared by their doctor. Any symptoms related to diabetic autonomic neuropathy should be followed up immediately instead of waiting until it becomes too late to reverse or arrest the effects.
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